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Sultamicillin Tosilate Dihydrate (eq. to Sulbactum 147 mg + Ampicillin 220 mg
- Sultamicillin is a semisynthetic double ester that combines ampicillin with the beta-lactamase inhibitor sulbactam
- Hydrolyzed in the gastrointestinal tract after oral administration to release equimolar quantitites of ampicillin and sulbactam
- To be effective against a wide range of gram-positive & gram-negative bacteria
- The combination of sulbactam with the beta-lactam antibiotic ampicillin restores the bactericidal activity of ampicillin
- The mutual prodrug effect of sultamicillin results from it having a more efficient oral absorption of ampicillin (3.5 folds more) than plain ampicillin
- Sultamicillin has increased bio availability as compared to Ampicillin
- Enables a convenient BID dosing
Indication:
- Genito-urinary tract infections
- Gastro-intestinal tract infections
- Skin and soft tissue infections
- Meningitis
- Respiratory tract infections
- Gonorrhoea